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Los Angeles, CA – GLP-1 medications are proving effective in weight loss, but experts emphasize that lasting results require a significant shift in lifestyle habits, according to endocrinologist Dr. Ana Maria Kausel.

Dr. Kausel explains that the body naturally attempts to return to its previous weight after initiating GLP-1 treatment. This inherent physiological response underscores the importance of adopting sustainable lifestyle modifications alongside medication.

“The body ‘always’ tries to revert to the weight it had before the patient started taking the medication,” Dr. Kausel stated. This highlights a crucial point: GLP-1 drugs are tools to assist weight management, not standalone solutions. Without concurrent changes in diet and exercise, the body will likely resist the weight loss achieved through medication alone.

The rise in popularity of GLP-1 receptor agonists, such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), has been significant. These medications work by mimicking hormones that regulate appetite and blood sugar, leading to reduced food intake and weight loss. However, the body’s adaptive mechanisms mean that relying solely on the medication is unlikely to result in long-term success.

Dr. Kausel’s advice reinforces the need for a holistic approach to weight management, integrating medication with a commitment to healthier eating patterns, regular physical activity, and behavioral changes. Patients considering or taking GLP-1 medications should consult with their healthcare providers to develop a comprehensive plan that addresses both pharmacological and lifestyle factors for optimal and sustained weight management.